This is an indica-dominant strain (35:65 sativa/indica ratio) best used late in the day. Though it comes with a head buzz that belies its indica genes, Skunk #1 also provides deep-body relaxation. The head high is energetic and creative, while the body high is peaceful and soothing. It can be used to treat anxiety and other mental disorders, as well as chronic pain, headaches, and lack of appetite.